PULMONARY CHEMORECEPTORS

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Chemoreceptors in bacteria.

For a hundred years it was known that motile bacteria are attracted to a variety of small organic molecules. However, few scientists were interested in bacterial chemotaxis, probably because they were unwilling to believe that these lowly organisms possessed any capability for information processing or could exhibit even simple forms of behavior. Despite evidence to the contrary, it was general...

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Flexible Hinges in Bacterial Chemoreceptors.

Transmembrane bacterial chemoreceptors are extended, rod-shaped homodimers with ligand-binding sites at one end and interaction sites for signaling complex formation and histidine kinase control at the other. There are atomic-resolution structures of chemoreceptor fragments but not of intact, membrane-inserted receptors. Electron tomography of in vivo signaling complex arrays lack distinct dens...

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Physical responses of bacterial chemoreceptors.

Chemoreceptors of the bacterium Escherichia coli are thought to form trimers of homodimers that undergo conformational changes upon ligand binding and thereby signal a cytoplasmic kinase. We monitored the physical responses of trimers in living cells lacking other chemotaxis proteins by fluorescently tagging receptors and measuring changes in fluorescence anisotropy. These changes were traced t...

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Renal chemoreceptors in the rat.

There are afferent nerve fibers responsive to alterations of the kidney's chemical environment in the renal nerves of the rat. In anesthetized, artificially ventilated, male Sprague-Dawley rats, single unit recordings were prepared by dissection of the centrally cut nerves of the right kidney. The stimuli used included occlusion of the renal artery, systemic asphyxia, changes in renal arterial ...

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Thoracic Chemoreceptors in the Dog

Anatomical and electrophysiological techniques were employed to investigate the aortic bodies in anesthetized puppies and dogs. The microscopic appearance, location, innervation, and vasculature of the aortic bodies were investigated by microdissection and histological examination of gelatineinjected preparations. Thoracic chemoreceptor impulses were recorded from the cervical vagus nerves, the...

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ژورنال

عنوان ژورنال: Quarterly Journal of Experimental Physiology and Cognate Medical Sciences

سال: 1963

ISSN: 0033-5541

DOI: 10.1113/expphysiol.1963.sp001647